During the events prior to the game's main storyline, Ryder was interrogated to test his loyalty to his country by being presented with photographs of individuals which he was asked if he would agree to kill without question (one of which was his wife, Emily White, which he agreed to reluctantly). After passing the test, Ryder was deployed on Banoi in order to aid which containing the recent infection outbreak. During the mission, Ryder and his squad on board of a helicopter were ordered to initiate a bombing run on the highway in the jungle.
During their flight back to base, the copilot of the aircraft became Infected and attacked the other pilot; forcing the craft to crash land in Moresby. Ryder later awakens from the crash several hours later to discover that he is the lone survivor of his crew. He is then contacted by the B.I.D.F. who instruct him to regroup with B.I.D.F. Unit 4 stationed near Saint Christopher's Church as the evacuation zone he requested pick up from had already departed. Ryder later arrives at the unit's location to discover that everyone had been killed by the local gang known as the Raskols before being stripped of their weapons and equipment which included the explosive charges needed to destroy the City Bridge in Sector 4 (Old Town) in order to prevent the Infection from spreading any further.
He is then informed by the B.I.D.F. to make his way to the Police Station in Sector 3 of the city in order to recover the explosives to complete Unit 4's mission. After fighting his way to the Police Station, Ryder is confronted by members of the gang who taunt him over the loss of his fellow soldiers. After a heated firefight, Ryder managed to kill the gang members and collected the stolen equipment before being instructed to proceed with finding and destroying the bridge. With most of the roadways blocked, Ryder climbed into a manhole that took him to the sewers beneath Moresby in order to gain access to the riverside.
Upon exiting the sewers, Ryder's progress is again faltered by a group of Raskols that claim the City Bridge as their territory; leaving him with no other option but to kill more civilians which the B.I.D.F. intel allowed in order to ensure the missions completion. With the gang members disposed of, Ryder proceeded with planting the charges on the bridge and demolishing the bridge. With the mission accomplished, the B.I.D.F. intel ordered Ryder to make his way to the evacuation zone in Sector 6 (Gas Station). Ryder then fought through waves of Infected as he waited for the evac chopper to arrive.
While on board the chopper, Ryder contacted Emily telling her to prepare herself to be picked up. Emily however, replied saying that she had been bitten by a patient and told Ryder to go on without her before making her tearful farewell to him. Unable to accept the loss of his wife, Ryder ordered the pilot not to land on the aircraft carrier off the coast of the island and instead change course to the Prison in order to pick up his wife (disregarding her advice). The chopper then landed on the roof of the prison where Ryder frantically sprinted his way inside to find Emily in hopes of not being too late.
When Ryder reaches Emily in the hospital wing of the prison, he finds her strapped to a bed trying to tell him to leave her in broken English as a result of the gradual transformation into an Infected. Ryder then travels deeper into the prison in order to find Kevin. Upon discovering Kevin, he discovers that Kevin is actually the hacker, Charon. Ryder was then left with no other choice but to collaborate with Charon in order to ensure his wife's life. Charon instructed Ryder to active the prison's emergency power in order to activate the complex's surveillance cameras which Charon would then use to guide Ryder. Once the power was back online, Ryder was confronted by a groups of rebel prisoners that managed to obtain firearms from the prison's armory. After fighting through numerous groups of prisoners, Ryder arrived at one of the other medical wards in the hospital where he found an antibiotic to slow the effects of the infection on Emily known as, Tetracycline. Once Ryder obtained the antibiotic, Charon informed him that the Heroes were on their way to the island with the antidote and that the antibiotic would slow down the effects of the infection on Emily until they arrived.
After administering the antibiotic to Emily, Charon notifies him that a group of prisoners were approaching in retaliation for the ones that Ryder killed in order to obtain the Tetracycline. With the prisoners dead, Ryder traveled to the control room in Block C and met up with Charon. As Ryder approaches Charon, he discovers that Charon was behind the deaths of the scientists at the Laboratory but hides his suspicion. He is then instructed to clear the infected from the shower room in Block C for when the Heroes arrive. With the shower room cleared, Ryder used the sewers in order to return to the control. While eavesdropping on Charon's conversation with the Heroes, he discovers that Charon has been posing as him (the Voice). Out of rage, Ryder threatens to kill Charon for endangering Emily and making him betray his country. Charon then ensures him that the Heroes have the "antidote" and that the Heroes won't trust either Ryder or Charon if it is revealed that they were never actually speaking to Ryder.
Charon then instructs Ryder to store knockout gas above the elevator lift that the Heroes will be using in order to steal the antidote from them to avoid having to make any negotiations. After placing the gas and returning to the control room, Charon and Ryder watch the Heroes pass out from the gas. Before leaving to retrieve the gas, Ryder destroys the control room's computer in order to prevent Charon from pulling off anymore tricks. He then locks Charon in the control room and tells him that he's going to go get the antidote form Emily. Charon the replied to Ryder stating that the antidote would only work on people that were only in the early stages of Infection while Emily was already past the first stages. Shaken by his words, Ryder ran off to get back to Emily in the intensive care unit. With Ryder gone, Charon reveals that he had a hidden backup key card and taunts him stating that Ryder should have killed him when he had the chance.
Afraid of being too late, Ryder collected the antidote from the Heroes and frantically fought through countless waves of Zombies to get back to Emily. Upon finding Emily, she has already become an Infected. Ryder then vows to make a complete antidote out of the serum and brings Emily to the roof where he discovers that Charon had turned the Heroes against him. Jin then releases Emily to attack Ryder, forcing him to kill her. He then injects himself with the antidote only to discover that the antidote was actually an enhanced version of the virus that transformed him into a powerful Special Infected. He is then killed by the Heroes. The Heroes get away on Ryder's chopper and it is revealed that Charon plans on using Yerema as Dr. West called, "a ticking time bomb" to spread the Infection.
Source : deadisland.wikia.com
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